Cryptotanshinone是什么

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August undefined, 2024

WebApr 18, 2024 · Cryptotanshinone (CTs), an active component isolated from the root of Salvia miltiorrhiza (SM), has been shown to exert potent neuroprotective property. We here established an oxygen-glucose deprivation/recovery (OGD/R)-injured Neurovascular Unit (NVU) model in vitro to observe the neuroprotective effects of CTs on cerebral … WebCryptotanshinone (CPT) is a natural compound extracted from herbal medicine that has been previously shown to possess antitumor properties in various types of human cancer cells. In the present study, we examined the potential role of CPT in the treatment of colorectal cancer. Using SW480, HCT116, a …

Cryptotanshinone C19H20O3 - PubChem

WebNov 11, 2008 · Abstract. Tanshinones are the major bioactive compounds of Salvia miltiorrhiza Bunge (Danshen) roots, which are used in many therapeutic remedies in Chinese traditional medicine. We investigated the anticancer effects of tanshinones on the highly invasive human lung adenocarcinoma cell line, CL1-5. Tanshinone I significantly inhibited … WebOct 5, 2024 · Results. In CT26 tumor-bearing mice, cryptotanshinone (20 and 60 mg/kg) administration drastically prevented systemic cancer cachexia from whole body weight loss and wasting of multiple tissues including heart, fat and skeletal muscle, with a negligible effect on cancer growth at dose of 20 mg/kg cryptotanshinone administration prevented … ontario to taiwan flight

Cryptotanshinone = 98 HPLC 35825-57-1 - Sigma-Aldrich

WebNational Center for Biotechnology Information WebAug 23, 2024 · Cryptotanshinone (Cry) has multiple potential functions in treating different diseases. Most studies on Cry focus on its pharmacological effects and mechanisms, but toxicological reports on Cry are rare. Zebrafish is used as a model organism in drug development as it saves costs and time. This work aimed to investigate the toxicity of Cry … WebCryptotanshinone (CTS) is a natural compound involved in antioxidant and anti-inflammatory activities. We evaluated the effects of CTS on inflammation and oxidative stress in obstructed kidneys. Mice received gastric gavage of CTS from 7 days before unilateral ureteral obstruction operation to 1 week after surgery. Administration of CTS at … ontario tourism strategy

Cryptotanshinone: A review of its pharmacology activities and ... - Pub…

隐丹参酮_化工百科

WebDec 30, 2024 · Cryptotanshinone (CT), a diterpene that is isolated from Salvia miltiorrhiza Bunge, exhibits anti-cancer, anti-oxidative, anti-fibrosis, and anti-inflammatory properties. Here, we examined whether CT administration possess a hepatoprotective effect on chronic ethanol-induced liver injury. We established a chronic alcohol feeding mouse model ... WebCryptotanshinone 隐丹参酮. CAS: 35825-57-1. 分子式: C 19 H 20 O 3. 分子量: 296.37. 外观（性状）: Orange Solid. 储存条件: Powder : 2-8℃, 2 years; In solvent (母液): -20℃, 1 … ionic homepageWebCryptotanshinone 是一种STAT3抑制剂，无细胞试验中IC50为4.6 μM，强烈抑制STAT3 Tyr705磷酸化，对STAT3 Ser727作用效果弱，对STAT1和STAT5没有作用效果 … ionic hooded dryer

"WebMar 2, 2024 · Cryptotanshinone (CPT), as a major component of Salvia miltiorrhiza Bunge (Danshen), displays many pharmacological activities including anti-inflammatory effects. However, the exact cellular and molecular mechanisms of the anti-inflammatory activities of CPT remain to be elucidated. The present study was aimed to clarify its mechanisms on … " - Cryptotanshinone是什么

Cryptotanshinone是什么

Cryptotanshinone: A review of its pharmacology activities and ... - PubMed

WebCryptotanshinone is a quinoid diterpene isolated from the root of the Asian medicinal plant, Salvia miotiorrhiza bunge. Recently it was discovered that the compound is a potent … WebIn this review, we intend to summarize the anti-cancer properties of Cryptotanshinone (CPT), an extract of Danshen (the root of Salvia miltiorrhiza Bunge), on different types of cancer. Cancer is among the most life-threatening diseases worldwide. Along with conventional therapies like chemotherapy, surgery, and radiotherapy, alternative ...

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WebMar 10, 2024 · Cryptotanshinone (CTS) is a lipophilic constituent of Salvia miltiorrhiza, with a broad-spectrum anticancer activity. We have observed that CTS enhances the efficacy of gefitinib in human lung cancer H1975 cells, yet little is known about its molecular mechanism. To explore how CTS enhances H1975 cell sensitivity to gefitinib, we figured … WebCryptotanshinone C19H20O3 CID 160254 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, …

WebMar 9, 2005 · Tanshinones including cryptotanshinone, tanshinone I and tanshinone IIA were successfully separated on a Diamonsil C18 column (150 mm x 4.6 mm i.d., 5 … WebMar 19, 2024 · The antitumor mechanism of CT. Cryptotanshinone inhibits the proliferation of cancer cells and induces autophagy and apoptosis by inhibiting IGF-1, IL-6, and …

WebCryptotanshinone (CT), one major lipophilic component isolated from Salvia miltiorrhiza Bunge, has shown to possess chemopreventive properties against various types of … WebAug 13, 2024 · Hepatocellular carcinoma (HCC) is a fatal and dominant form of liver cancer that currently has no effective treatment or positive prognosis. In this study, we explored the antitumor effects of cryptotanshinone (CPT) against HCC and the molecular mechanisms underlying these effects using a systems pharmacology and experimental validation …

Web它不仅影响AR功能，也能显著抑制AR转录活性和AR靶基因在mRNA和蛋白质水平表达，同时还阻断AR和赖氨酸一特异性脱甲基酶一1LSD1)之间的相互作用，抑制AR的靶基因启动子，增加了组蛋白H3赖氨酸9 (H3K9)的单甲基和二甲基化。. 丹参有效成分. 隐丹参酮 (cryptotanshinone ...

WebCryptotanshinone is a quinoid diterpene isolated from the root of the Asian medicinal plant, Salvia miotiorrhiza bunge. Recently it was discovered that the compound is a potent STAT3 inhibitor. Cryptotanshinone rapidly inhibited STAT3 Tyr705 phosphorylation through a JAK2-independent mechanism. Cryptotanshinone selectively inhibits STAT3 ... ionic hide scrollbarWeb隐丹参酮(cryptotanshinone)是从唇形科植物丹参的干燥根及根茎中提取的一种二萜醌类化合物，为活血化瘀药丹参脂溶性成分中的代表性成分，具有抗雄性激素过多分泌，杀死痤疮 … ontario to winnipeg timeWebAug 13, 2024 · Results: The combination of fosfomycin and cryptotanshinone had a synergistic effect on most (71.43%) of the FRSA and had a partial (28.57%) synergistic effect on a small part. In addition, time sterilization curve verified synergistic activity between cryptanshinone and fosfomycin against FSSA and FRSA, especially when fosfomycin was … ontario townhouses 1360 e d stWebNational Center for Biotechnology Information ontario to west covinaWebJul 1, 2024 · Abstract. Cryptotanshinone is a diterpene quinone derived from the roots of Salvia miltiorrhiza Bunge. An increasing number of studies have demonstrated that cryptotanshinone has the pharmacological activities such as anti-oxidative stress, anti-bacteria, anti-inflammation, and anti-cancer. Cryptotanshinone has been found to … ontario townhouses for saleWebMar 19, 2024 · Cancer is a common malignant disease worldwide with an increasing mortality in recent years. Salvia miltiorrhiza, a well-known traditional Chinese medicine, has been used for the treatment of cardiovascular and cerebrovascular diseases for thousands of years. The liposoluble tanshinones in S. miltiorrhiza are important bioactive … ontario to seattle flights non-stopWebTanshinone IIA, cryptotanshinone and tanshinone I are the main antitumor ingredients of Salvia miltiorrhiza. The antitumor mechanisms of tanshinone IIA are as follows: (1) … ontario tourist attractions ontario canada