WebKim et al. show cell-type-specific properties of spatial firing in the dentate gyrus by recording from single cells as mice freely explored distinct environments. These findings support the role of both granule cells and mossy cells in global remapping and orthogonalization (pattern separation) of spatial representations in dentate gyrus. WebFeb 3, 2024 · Mossy cells (MCs) of the dentate gyrus (DG) are a major group of excitatory hilar neurons that are important for regulating activity of dentate granule cells. MCs are particularly intriguing because of their extensive longitudinal connections within the DG. It has generally been assumed that MCs in the dorsal and ventral DG have similar patterns …
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WebSep 24, 2024 · Several studies suggest that neurons from the lateral region of the SuM (SuML) innervating the dorsal dentate gyrus (DG) display a dual GABAergic and … WebJan 1, 2024 · Multiple studies have found evidence of abnormal dentate gyrus network circuitry in human mesial temporal lobe epilepsy (MTLE). Principal neurons within the … how to check if your licence is disqualified
Factors Regulating Neurogenesis in the Adult Dentate Gyrus
WebAug 9, 2012 · Protein levels of synaptophysin in dentate gyrus were significantly deflated in the stressed, ischemic and MCAO+CMS individuals compared to the controls (P<0.05). Furthermore, there was a decrease in synaptophysin protein expression in the MCAO+CMS animals compared to the ischemia rats (P<0.05). WebFurthermore, in the dentate gyrus, progenitor cells of the secondary dentate matrix migrate to the hilus and establish the tertiary dentate matrix. During the late postnatal period, the progenitors of the tertiary dentate matrix are gradually confined to the SGZ, which contains adult stem cell-like cells. WebFeb 20, 2008 · Research in humans and animals has shown that exercise improves mood and cognition. Physical activity also causes a robust increase in neurogenesis in the … how to check if your laptop is hacked